abstract：BACKGROUND:Fragmented QRS complexes (fQRS) have been associated with increased morbidity and mortality, sudden cardiac death, and recurrent cardiovascular events. The association between left ventricular systolic and diastolic functions and presence of fragmented QRS has not been comprehensively studied to date. We tes...

journal_title：Herz

authors： Canga A,Kocaman SA,Durakoğlugil ME,Cetin M,Erdoğan T,Kırış T,Erden M

更新日期：2013-09-01 00:00:00

abstract：:Chronic heart failure has an age-dependent prevalence of 2% and is therefore one of the most frequent diseases in western societies. A reduced hemoglobin concentration according to the definition of the World Health Organization is a common comorbidity affecting more than half of all heart failure patients. Elderly pa...

journal_title：Herz

authors： Reda S,Motloch LJ,Hoppe UC

更新日期：2013-09-01 00:00:00

abstract：:Coronary artery disease (CAD) is a leading cause of morbidity and mortality in western countries and is of significant socio-economic importance due to its increasing prevalence. Until percutaneous coronary interventions (PCI) were established, CAD could only be treated by surgical revascularization or pharmacological...

journal_title：Herz

authors： Möllmann H,Szardien S,Kempfert J,Nef H,Liebetrau C,Walther T,Hamm C

更新日期：2013-08-01 00:00:00

abstract：:In patients with chronic coronary artery disease different therapeutic strategies, such as optimal medical therapy, revascularization by percutaneous coronary intervention or coronary artery bypass grafting have been shown to improve the prognosis and symptoms and yield proven superiority over other treatment strategi...

journal_title：Herz

authors： de Waha S,Eitel I,Desch S,Fuernau G,Lurz P,Schuler G,Thiele H

更新日期：2013-06-01 00:00:00

abstract：:Dyspnea is one of the major clinical symptoms which patients report to general practitioners, internists, cardiologists and hospitals. In this review article we discuss the evidence of medical history, laboratory procedures and diagnostic investigations to approach patients with acute or chronic dyspnea and try to str...

journal_title：Herz

authors： Henke MO,Vogelmeier CF

更新日期：2013-05-01 00:00:00

abstract：BACKGROUND AND AIM OF THE STUDY:The predisposition to atrial fibrillation (AF) in mitral stenosis (MS) has been demonstrated with several electrocardiographic (increased P-wave dispersion) and echocardiographic parameters (atrial electromechanical delay). Despite the improvement in P-wave dispersion after percutaneous ...

journal_title：Herz

authors： Demirkan B,Guray Y,Guray U,Ege MR,Kisacik HL,Sasmaz H,Korkmaz S

更新日期：2013-03-01 00:00:00

abstract：:Diastolic heart failure, also known as heart failure with preserved left ventricular ejection fraction (HF-pEF), is responsible for approximately 50 % of all heart failure cases. According to current guidelines the diagnosis HF-pEF requires three criteria: (1) signs or symptoms of heart failure, (2) presence of a norm...

journal_title：Herz

authors： Weidemann F,Niemann M,Herrmann S,Ertl G,Störk S

更新日期：2013-02-01 00:00:00

abstract：:The term diabetic cardiomyopathy was initially introduced in the 1980s when evidence was found that diabetes leads to a distinct cardiomyopathy, independent of coronary artery disease or hypertension. The detection of diabetic cardiomyopathy using echocardiography is challenging because no pathognomonic signs exist; h...

journal_title：Herz

authors： Niemann M,Herrmann S,Ertl G,Weidemann F

更新日期：2013-02-01 00:00:00

abstract：:Eosinophilic myocarditis is caused by activation of eosinophilic granulocytes whereby there is a release of eosinophilic granules. Quite a few of the released compounds, especially eosinophilic cationic proteins, have a tissue-damaging effect also in the myocardium. Eosinophilia may be due to hypersensitivity, parasit...

journal_title：Herz

authors： Baandrup U

更新日期：2012-12-01 00:00:00

abstract：:While there is general agreement on the favorable impact of immunosuppression in eosinophilic, granulomatous, giant cell and lymphocytic myocarditis and with inflammatory myocardial disease associated with connective tissue disorders or with rejection of a transplanted heart, its therapeutic role in the treatment of l...

journal_title：Herz

authors： Frustaci A,Chimenti C

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:Atrial fibrillation (AF) recurrence after ablation is difficult to predict. The development of AF is associated with inflammation, and inflammatory markers such as big endothelin-1 (big ET-1) reflect inflammatory status. It is unknown, however, whether big ET-1 can be used as a predictor for AF recurrence. T...

journal_title：Herz

authors： Wang H,Liu J,Fang P,Lei S,Li X,Hou Y,Zhang S

更新日期：2012-12-01 00:00:00

abstract：:Familial dilated cardiomyopathy (F-DCM) describes a clinically and genetically heterogeneous group of diseases, mostly inherited as autosomal dominant traits, having idiopathic left ventricular dilatation and dysfunction as a common phenotype. The age of onset, rate of progression, disease complications, as well as ov...

journal_title：Herz

authors： Serio A,Narula N,Kodama T,Favalli V,Arbustini E

更新日期：2012-12-01 00:00:00

abstract：OBJECTIVE:The aim of this study was the analysis of long-term results in patients with hemodynamically significant mitral valve disease due to extensively calcified mitral annulus who underwent decalcification and patch reconstruction. PATIENTS AND METHODS:Between 1996 and 2008 a total of 109 patients underwent surger...

journal_title：Herz

authors： Steuer K,Papadopoulos N,Moritz A,Doss M

更新日期：2012-11-01 00:00:00

abstract：:Via the internet smartphones allow the download of applications ("Apps") that can address various requirements of daily life. These technical advances create new opportunities to better meet needs of patients suffering from hypertension. This may apply particularly for medication adherence, blood pressure control and ...

journal_title：Herz

authors： Becker S,Mitchell A,Königsmann T,Kribben A,Erbel R

更新日期：2012-11-01 00:00:00

abstract：:Henoch-Schönlein purpura (HSP) is characterized by vasculitic involvement of small-sized vessels and results in multisystem manifestations. Cardiac involvement is extremely rare and myocardial infarction with coronary thrombus formation in those patients has also rarely been reported. Herein, we report a 33-year-old m...

journal_title：Herz

authors： Canpolat U,Yorgun H,Sahiner L,Kabakçi G

更新日期：2012-11-01 00:00:00

abstract：:The diagnosis of constrictive pericarditis should be considered in any patient with unexplained right heart failure. The differentiation between constrictive pericarditis and restrictive cardiomyopathy is based on a combination of clinical presentation, history and imaging, and on occasion, on the basis of invasive he...

journal_title：Herz

authors： Zwas DR,Gotsman I,Admon D,Keren A

更新日期：2012-09-01 00:00:00

abstract：:Acute myocarditis is a major inflammatory heart disease with a variety of clinical courses from the acute to chronic phases represented by unexpected circulatory deterioration during hospitalization and progression to dilated cardiomyopathy. Predicting these disease courses is important for patient management. However...

journal_title：Herz

authors： Izumi T,Nishii M

更新日期：2012-09-01 00:00:00

abstract：:Remodelling is the adaptive or maladaptive response to cardiac overload or injury resulting in changes of size and function of the heart. The final pathway of maladaptive or adverse cardiac remodelling is the evolution of heart failure or sudden cardiac death. In coronary artery disease, ischemic injury leads to chang...

journal_title：Herz

authors： Brenner S,Ertl G

更新日期：2012-09-01 00:00:00

abstract：:Pulmonary arteriovenous malformations (PAVM) consist of an abnormal connection between the pulmonary artery and vein bypassing the pulmonary capillary bed. Pulmonary arteriovenous fistulae are characterized by a right-to-left shunt of variable magnitude, and they may be accompanied by other congenital anomalies. We de...

journal_title：Herz

authors： Kucukoglu MS,Sinan UY,Kilickesmez KO,Saltık IL,Dursun M,Gurmen T

更新日期：2012-08-01 00:00:00

abstract：:The standardized and constant fixed-dose rate, no necessity for a close and regular blood monitoring as well as the small number of interactions with other drugs and daily food make therapy with the new oral anticoagulants dabigatran and rivaroxaban and in future presumably apixaban much easier and more feasible than ...

journal_title：Herz

authors： Osterspey A,Krome A

更新日期：2012-06-01 00:00:00

abstract：:Although rarely reported, acute instent thrombosis can be life threatening, especially in cases where there are no ST segment changes. For this reason, careful history taking, follow-up, and prompt coronary angiography may be lifesaving. Herein, a case of acute stent thrombosis with no ST segment changes on electrocar...

journal_title：Herz

authors： Canpolat U,Sunman H,Yorgun H,Atalar E

更新日期：2012-05-01 00:00:00

abstract：:The case presented here is intended to raise awareness of two uncommon coronary angiographic findings in the clinical context of acute coronary syndrome. The prevalence of patients presenting with spontaneous coronary dissection as the underlying cause of an ST-elevation myocardial infarction is low. It is typically f...

journal_title：Herz

authors： Hofmann U,Schanzenbächer P

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:Causes of pericardial effusion requiring pericardiocentesis are very complex; a summary of 140 patients, especially those having iatrogenic pericardial effusion, is rare. METHODS:We prospectively analyzed the clinical data and etiology of moderate to large pericardial effusion requiring pericardiocentesis a...

journal_title：Herz

authors： Ma W,Liu J,Zeng Y,Chen S,Zheng Y,Ye S,Lan L,Liu Q,Weig HJ,Liu Q

更新日期：2012-03-01 00:00:00

abstract：:Atrial fibrillation represents the most common form of clinical arrhythmia in daily routine. However, current therapeutic options are still limited and a better understanding of the underlying molecular mechanisms is expected to contribute to the development of new therapeutic strategies. The scientific field of micro...

journal_title：Herz

authors： Wakili R,Clauß S,Kääb S

更新日期：2012-03-01 00:00:00

abstract：:Reducing cardiac mortality and improving quality of life are the main objectives of cardiac rehabilitation. In recent years, outpatient rehabilitation within easy patient reach has achieved the same status as inpatient rehabilitation. Outpatient rehabilitation permits close involvement of the patient's family and soci...

journal_title：Herz

authors： Fischer HM,Charrier A,Dörr R,Spitzer SG

更新日期：2012-02-01 00:00:00

abstract：:Myocardial remodeling comprises changes in cardiac shape, mass, diameter, and function in response to changes in hemodynamic load, cardiac damage, or neurohumoral stimulation. Adaptive remodeling is a consequence of physiological stimuli such as physical activity. Maladaptive remodeling results from pathologic conditi...

journal_title：Herz

authors： Werner C,Fürster T,Laufs U

更新日期：2012-02-01 00:00:00

abstract：:Atrial fibrillation represents the most common atrial arrhythmia seen in clinical practice. The surgical treatment of atrial fibrillation is recommended in symptomatic patients as well as in asymptomatic patients at low postoperative risk. As a "stand alone" procedure, surgical ablation therapy is indicated after fail...

journal_title：Herz

authors： Hanke T,Sievers HH

更新日期：2011-12-01 00:00:00

abstract：:Cardiac contractility modulation (CCM) is a device therapy for patients with systolic heart failure. CCM therapy applies non-excitatory signals during the absolute refractory period of the heart cycle. It influences myocardial contractility by modulating the regulation of calcium cycling. CCM therapy has been proven t...

journal_title：Herz

authors： Tönnis T,Kuck KH

更新日期：2011-10-01 00:00:00

abstract：:Marfan syndrome is a hereditary disease with a prevalence of 2-3 in 10,000 births, leading to a fibrillin connective tissue disorder with manifestations in the skeleton, eye, skin, dura mater and in particular the cardiovascular system. Since other syndromes demonstrate similar vascular manifestations, but therapy may...

journal_title：Herz

authors： Kallenbach K,Schwill S,Karck M

更新日期：2011-09-01 00:00:00

abstract：:Non-invasive tomographic imaging modalities have recently contributed to identifying aortic intramural hematoma, a variant form of classic dissection, which is characterized by the absence of an intimal tear and thus the absence of direct flow communication, and which represents an important disease entity in acute ao...

journal_title：Herz

authors： Song JK

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:Left ventricular inferoseptal clefts are a localized variant of myocardial structure, easily overlooked but potentially raising concern when identified through imaging. CASE STUDY:Here we illustrate and describe inferoseptal clefts by means of multimodality imaging and consider them in relation to possible ...

journal_title：Herz

authors： Wein M,Wolf-Puetz A,Niehues R,Klein T,Kilner PJ,Klein RM

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND:The differential diagnosis of pericardial effusion is often challenging because different etiologies can be discussed. Of particular therapeutic and prognostic importance is the definitive differentiation of malignant pericardial effusion from benign effusions. The definitive diagnosis of malignant pericardi...

journal_title：Herz

authors： Karatolios K,Maisch B,Pankuweit S

更新日期：2011-06-01 00:00:00

abstract：:Doxorubicin is an effective anti-tumor agent with a cumulative dose-dependent cardiotoxicity. In addition to its principal toxic mechanisms involving iron and redox reactions, recent studies have described new mechanisms of doxorubicin-induced cell death, including abnormal protein processing, hyper-activated innate i...

journal_title：Herz

authors： Shi Y,Moon M,Dawood S,McManus B,Liu PP

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND:The objective of the present review was to investigate the cost-effectiveness of second-generation drug-eluting stents (DES) compared to bare metal stents (BMS) as well as to first-generation DES. METHODS:A structured literature review in MEDLINE was conducted to identify all studies investigating the cost-...

journal_title：Herz

authors： Müller-Riemenschneider F,Reinhold T,Willich SN

更新日期：2011-05-01 00:00:00

abstract：:To account for the current evidence in the field of infective endocarditis and to harmonize deviant national guidelines, in 2009 the European Society of Cardiology published novel recommendations on the prevention, diagnosis and treatment of infective endocarditis.The most important changes can be found concerning ant...

journal_title：Herz

authors： Plicht B,Erbel R

更新日期：2010-12-01 00:00:00

abstract：:We present a case of severe congestive left heart failure due to profound and long-term hypocalcemia caused by surgically induced hypoparathyroidism. Hypocalcemia as a potential contributor to heart failure should be included in the differential diagnosis of all patients with congestive heart failure who do not respon...

journal_title：Herz

authors： Solzbach U,Kitterer HR,Haas H

更新日期：2010-10-01 00:00:00

abstract：:Chronic ischemic heart disease patients are already being treated worldwide with bone marrow stem cells both in the context of clinical studies and in therapy trials. By combining this therapy with established revascularization procedures such as bypass surgery, a high level of patient safety can be achieved. To date,...

journal_title：Herz

authors： Kaminski A,Donndorf P,Klopsch C,Steinhoff G

更新日期：2010-08-01 00:00:00

abstract：:Cardiac function, including the heart muscle and valves, can be severely altered by congenital and acquired heart diseases. Several graft materials are currently used to replace diseased cardiac tissue and valvular segments. Implantable grafts are either non-vital or can trigger an immune response which leads to graft...

journal_title：Herz

authors： Cebotari S,Tudorache I,Schilling T,Haverich A

更新日期：2010-08-01 00:00:00

abstract：:At present, in patients with diabetes mellitus and coronary multivessel disease no fixed general recommendation can be given in favor or to the disadvantage of surgical revascularization or in favor or to the disadvantage of percutaneous coronary intervention (PCI). In cases with an evidence-based indication for coron...

journal_title：Herz

authors： Dörr R

更新日期：2010-05-01 00:00:00

abstract：:According to the current guidelines coronary revascularization in acute coronary syndromes (ACS) is primarily performed by percutaneous coronary interventions (PCI). However, in several scenarios like complex coronary pathologies, unsuccessful PCI, complicated PCI or cardiogenic shock, surgical coronary revascularizat...

journal_title：Herz

authors： Rastan AJ,Thiele H,Schuler G,Mohr FW

更新日期：2010-03-01 00:00:00